Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138789 | 0.87 | LPL (0.38) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL21666040 | 0.87 | LPL (0.38) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL19747926 | 0.84 | LPL (0.36) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL22095433 | 0.77 | LPL (0.40) | LPLLIPGJAK2BTKEGFR | |
| SCHEMBL897058 | 0.76 | LPL (0.50) | LPLLIPGJAK2BTKEGFR | |
| SCHEMBL21042445 | 0.76 | LIPG (0.50) | LPLLIPGJAK2BTKEGFR | |
| SCHEMBL29424567 | 0.76 | LPL (0.50) | LPLLIPGJAK2BTKEGFR | |
| SCHEMBL37395635 | 0.75 | LPL (0.41) | LPLLIPGJAK2BTKEGFR | |
| SCHEMBL6120636 | 0.75 | LPL (0.41) | LPLLIPGJAK2BTKEGFR | |
| SCHEMBL17491867 | 0.75 | LPL (0.53) | LPLLIPGEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666541-B | Purine or deazapurine derivatives for the treatment of, in particular, viral infections | GILEAD SCIENCES, INC. (US) | 2015-11-25 | — | — | CN | disclosed |