Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.65 |
| ▸ | FLT3 | P36888 | 13/20 | 0.65 |
| ▸ | KIT | P10721 | 10/20 | 0.65 |
| ▸ | CSF1R | P07333 | 5/20 | 0.65 |
| ▸ | FLT1 | P17948 | 5/20 | 0.65 |
| ▸ | FLT4 | P35916 | 4/20 | 0.65 |
| ▸ | LCK | P06239 | 3/20 | 0.65 |
| ▸ | AURKA | O14965 | 3/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.53 |
| ▸ | LYN | P07948 | 3/20 | 0.53 |
| ▸ | BLK | P51451 | 3/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.53 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.53 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.53 |
| ▸ | RET | P07949 | 2/20 | 0.53 |
| ▸ | MET | P08581 | 2/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21668626 | 0.90 | KDR (0.56) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21668631 | 0.89 | KDR (0.72) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21668637 | 0.85 | KDR (0.60) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21668628 | 0.85 | KDR (0.50) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21386467 | 0.84 | KDR (0.61) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21668601 | 0.84 | KDR (0.61) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL423660 | 0.82 | KDR (0.81) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL419771 | 0.80 | KDR (1.00) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21386472 | 0.80 | KDR (0.60) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21668632 | 0.79 | KDR (0.61) | KDRFLT3KITCSF1RFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11351151-B2 | Compound having anticancer activity and preparation method and application | 3D MEDICINES (BEIJING) CO., LTD. (CN) | 2022-06-07 | — | — | US | disclosed |
| US-20200038371-A1 | COMPOUND HAVING ANTICANCER ACTIVITY AND PREPARATION METHOD AND APPLICATION | 3D MEDICINES (BEIJING) CO., LTD. (CN) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038371-A1 | COMPOUND HAVING ANTICANCER ACTIVITY AND PREPARATION METHOD AND APPLICATION | HDGF, MKI67, LITAF | KDR 421/4885FLT3 49/4885KIT 52/4885 |
| US-11351151-B2 | Compound having anticancer activity and preparation method and application | HDGF, MKI67, LITAF | KDR 440/4885FLT3 49/4885KIT 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.