SCHEMBL6587899

SCHEMBL6587899

CC1Nc2ccccc2NC1C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 5/20 0.50
BRPF1 P55201 1/20 0.50
BRD4 O60885 5/20 0.45
EP300 Q09472 1/20 0.45
MEN1 O00255 2/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.43
ALOX15 P16050 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
GFER P55789 1/20 0.43
NOS2 P35228 2/20 0.41
HTR5A P47898 4/20 0.39
PTPN1 P18031 1/20 0.38
IDO1 P14902 1/20 0.36
PARP1 P09874 1/20 0.35
RAB9A P51151 1/20 0.34
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570964 1.00 CREBBP (0.50) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL8279432 0.81 CREBBP (0.50) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL17376745 0.80 CREBBP (0.42) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL25506285 0.78 MEN1 (0.47) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL28168173 0.77 CREBBP (0.42) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL27321647 0.77 CREBBP (0.38) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL18269674 0.76 HTR5A (0.41) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL7571638 0.76 HTR5A (0.41) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL172934 0.76 HTR5A (0.41) CREBBPBRPF1BRD4EP300MEN1
SCHEMBL29501187 0.76 HTR5A (0.41) CREBBPBRPF1BRD4EP300MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012112758-A2 VIRTUAL HYDROGEN STORAGE PROCESSES AND RELATED CATALYSTS AND SYSTEMS YALE UNIVERSITY (US) 2012-08-23 WO claimed
CN-116751170-A Method for directly preparing semi-hydrogenated nitrogen-containing aromatic heterocyclic compound from sugar 浙江大学 2023-09-15 CN disclosed
US-11005051-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-05-11 US disclosed
US-20200403166-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2020-12-24 US disclosed
EP-3248230-B1 USE OF ORGANIC MOLECULES IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2020-05-06 EP disclosed
CN-106831565-B The restoring method of benzo aromatic aza cyclics 三峡大学 2019-11-08 CN disclosed
US-9812643-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2017-11-07 US disclosed
CN-106831565-A The restoring method of benzo aromatic aza cyclics 三峡大学 2017-06-13 CN disclosed
WO-2016116521-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed
WO-2016116517-A1 PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed
WO-2016116522-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed
WO-2016116524-A2 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed
WO-2016116518-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed
WO-2016116520-A1 PHENYLETHER-SUBSTITUTED ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed
WO-2016116487-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed
EP-3048155-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS cynora GmbH (DE) 2016-07-27 EP disclosed
EP-3048156-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS cynora GmbH (DE) 2016-07-27 EP disclosed
WO-2012112758-A2 VIRTUAL HYDROGEN STORAGE PROCESSES AND RELATED CATALYSTS AND SYSTEMS YALE UNIVERSITY (US) 2012-08-23 WO disclosed
EP-0746555-B1 HIGH TEMPERATURE EPOXY RESINS SECR DEFENCE (GB) 2004-06-30 EP disclosed
US-5710242-A High temperature epoxy resins from hydrogenated quinoxalines THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE EVALUATION RESEARCH AGENCY (GB) 1998-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11005051-B2 Organic electroluminescent materials and devices TAAR1, TRMT1L, TERT CREBBP 3910/4885BRPF1 3080/4885BRD4 2462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.