Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MGMT | P16455 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | FSHR | P23945 | 2/20 | 0.36 |
| ▸ | LHCGR | P22888 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20047063 | 0.86 | MGMT (0.43) | MMP2MMP9MMP8MMP13OPRM1 | |
| SCHEMBL21669658 | 0.81 | MGAM (0.41) | MMP2MMP9MMP8MMP13MGAM | |
| SCHEMBL24841212 | 0.81 | MAPT (0.46) | MGAMGAASIMGAM2GLA | |
| SCHEMBL18858993 | 0.78 | MGMT (0.47) | MMP2MMP9MMP8MMP13OPRM1 | |
| SCHEMBL15905756 | 0.77 | OPRM1 (0.40) | MMP2MMP9MMP8MMP13OPRM1 | |
| SCHEMBL27017059 | 0.77 | MGMT (0.45) | MMP2MMP9MMP8MMP13OPRM1 | |
| SCHEMBL30162890 | 0.76 | MGAM (0.38) | MGAMGAASIMGAM2GLA | |
| SCHEMBL20046973 | 0.76 | MMP2 (0.47) | MMP2MMP9MMP8MMP13OPRM1 | |
| SCHEMBL24569987 | 0.75 | MGMT (0.44) | MMP2MMP9MMP8MMP13OPRM1 | |
| SCHEMBL21643814 | 0.75 | OPRM1 (0.41) | MMP2MMP9MMP8MMP13OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039943-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039943-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SLC10A1, SLCO1B3, SLC5A1 | MMP2 2769/4885MMP9 1131/4885MMP8 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.