Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RHOA | P61586 | 2/20 | 0.48 |
| ▸ | RHOC | P08134 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TGM1 | P22735 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670330 | 0.94 | PTPN2 (0.60) | RAB9ANPC1ABL1RIN1PTPN2 | |
| SCHEMBL28578815 | 0.92 | RAB9A (0.54) | RAB9ANPC1ABL1RIN1PTPN2 | |
| SCHEMBL21670584 | 0.92 | RAB9A (0.54) | RAB9ANPC1ABL1RIN1PTPN2 | |
| SCHEMBL21669772 | 0.90 | RAB9A (0.53) | RAB9ANPC1MGLLALDH1A1RHOA | |
| SCHEMBL21670350 | 0.90 | RAB9A (0.53) | RAB9ANPC1MGLLALDH1A1RHOA | |
| SCHEMBL18045231 | 0.87 | RAB9A (0.55) | RAB9ANPC1ABL1RIN1PTPN2 | |
| SCHEMBL30507625 | 0.87 | RAB9A (0.55) | RAB9ANPC1ABL1RIN1PTPN2 | |
| SCHEMBL18045232 | 0.87 | RAB9A (0.55) | RAB9ANPC1ABL1RIN1PTPN2 | |
| SCHEMBL21670352 | 0.87 | RAB9A (0.52) | RAB9ANPC1MGLLKMT2AALDH1A1 | |
| SCHEMBL21669774 | 0.87 | RAB9A (0.52) | RAB9ANPC1MGLLKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028482-A1 | SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-02-06 | — | — | WO | disclosed |