SCHEMBL29620541

SCHEMBL29620541

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccoc3)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 13/20 0.58
CYP3A4 P08684 13/20 0.58
MEN1 O00255 8/20 0.58
KMT2A Q03164 8/20 0.58
CYP2D6 P10635 8/20 0.58
HSD17B10 Q99714 7/20 0.58
CYP2C19 P33261 7/20 0.58
MAPT P10636 5/20 0.58
ALOX15 P16050 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
USP2 O75604 9/20 0.54
CLK4 Q9HAZ1 7/20 0.54
ALDH1A1 P00352 5/20 0.54
TSHR P16473 6/20 0.53
LMNA P02545 5/20 0.53
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 2/20 0.48
MAPK1 P28482 2/20 0.48
ADORA2A P29274 3/20 0.46
ADORA1 P30542 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29925335 0.91 CYP1A2 (0.51) CYP1A2CYP3A4MEN1KMT2ACYP2D6
SCHEMBL29924790 0.89 CYP1A2 (0.50) CYP1A2CYP3A4MEN1KMT2ACYP2D6
SCHEMBL29620535 0.88 CYP1A2 (0.50) CYP1A2CYP3A4MEN1KMT2ACYP2D6
SCHEMBL22130013 0.88 CYP1A2 (0.50) CYP1A2CYP3A4MEN1KMT2ACYP2D6
SCHEMBL29620550 0.84 MEN1 (0.55) CYP1A2CYP3A4MEN1KMT2ACYP2D6
SCHEMBL29620537 0.79 KMT2A (0.52) CYP1A2CYP3A4MEN1KMT2ACYP2D6
SCHEMBL29993559 0.79 ADORA2A (0.63) CYP1A2CYP3A4MEN1KMT2ACYP2D6
SCHEMBL1126802 0.79 ALDH1A1 (0.50) CYP1A2CYP3A4MEN1KMT2ACYP2D6
SCHEMBL371042 0.78 L3MBTL1 (0.74) MEN1KMT2AMAPTALOX15ALDH1A1
SCHEMBL5781692 0.77 CTRC (0.48) CYP1A2CYP3A4MEN1KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853745-A Organic electroluminescent material and device 环球展览公司 2022-08-05 CN disclosed
CN-114555566-A Organic compound and organic electroluminescent element comprising same 索路思高新材料有限公司 2022-05-27 CN disclosed