SCHEMBL21670523

SCHEMBL21670523

CCOc1ccc(-c2cc(-c3ccc(Nc4ccc(CC)cc4)cc3)cc(-c3ccc(OCC)cc3OCC)n2)c(OCC)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40
TUBA1A Q71U36 1/20 0.40
TUBA1C Q9BQE3 1/20 0.40
TUBB6 Q9BUF5 1/20 0.40
TUBB2B Q9BVA1 1/20 0.40
TUBB1 Q9H4B7 1/20 0.40
ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525958 1.00 KDM4E (0.43) KDM4ELMNATP53SMN1; SMN2TUBB4A
SCHEMBL30525957 0.93 KDM4E (0.46) KDM4ELMNATP53SMN1; SMN2TUBB4A
SCHEMBL21670518 0.93 KDM4E (0.46) KDM4ELMNATP53SMN1; SMN2TUBB4A
SCHEMBL21670545 0.91 KDM4E (0.42) KDM4ELMNATP53SMN1; SMN2ALOX5
SCHEMBL30526021 0.91 KDM4E (0.42) KDM4ELMNATP53SMN1; SMN2ALOX5
SCHEMBL21670540 0.89 KDM4E (0.52) KDM4ELMNATP53SMN1; SMN2TUBB4A
SCHEMBL30525974 0.89 LMNA (0.47) KDM4ELMNATP53SMN1; SMN2TUBB4A
SCHEMBL21670537 0.89 LMNA (0.44) KDM4ELMNATP53SMN1; SMN2ALOX5
SCHEMBL21670570 0.89 LMNA (0.47) KDM4ELMNATP53SMN1; SMN2TUBB4A
SCHEMBL30525979 0.89 KDM4E (0.52) KDM4ELMNATP53SMN1; SMN2TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed