SCHEMBL21670537

SCHEMBL21670537

CCOc1ccc(-c2cc(-c3ccc(Nc4ccc(C)cc4)cc3)cc(-c3ccc(OCC)cc3OCC)n2)c(OCC)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
TP53 P04637 2/20 0.44
KDM4E B2RXH2 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
AGPAT2 O15120 2/20 0.43
GRM5 P41594 1/20 0.42
MAPT P10636 2/20 0.41
ENPP3 O14638 1/20 0.40
ENPP1 P22413 1/20 0.40
CACNA2D1 P54289 1/20 0.39
ALOX5 P09917 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 2/20 0.38
MAPK1 P28482 1/20 0.38
SLC2A1 P11166 1/20 0.38
SRC P12931 1/20 0.38
AURKA O14965 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525968 1.00 LMNA (0.44) LMNATP53KDM4ESMN1; SMN2AGPAT2
SCHEMBL30525957 0.94 KDM4E (0.46) LMNATP53KDM4ESMN1; SMN2AGPAT2
SCHEMBL21670518 0.94 KDM4E (0.46) LMNATP53KDM4ESMN1; SMN2AGPAT2
SCHEMBL21670540 0.91 KDM4E (0.52) LMNATP53KDM4ESMN1; SMN2AGPAT2
SCHEMBL30525979 0.91 KDM4E (0.52) LMNATP53KDM4ESMN1; SMN2AGPAT2
SCHEMBL21670570 0.91 LMNA (0.47) LMNATP53KDM4ESMN1; SMN2MAPT
SCHEMBL30525974 0.91 LMNA (0.47) LMNATP53KDM4ESMN1; SMN2MAPT
SCHEMBL21670523 0.89 KDM4E (0.43) LMNATP53KDM4ESMN1; SMN2AGPAT2
SCHEMBL30525958 0.89 KDM4E (0.43) LMNATP53KDM4ESMN1; SMN2AGPAT2
SCHEMBL21670522 0.89 MAPT (0.42) LMNATP53KDM4ESMN1; SMN2AGPAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed