Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19480811 | 0.85 | CHRNA1 (0.32) | CHRNA1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL14394656 | 0.82 | L3MBTL1 (0.33) | CHRNA1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9610944 | 0.80 | MEN1 (0.44) | — | |
| SCHEMBL24033649 | 0.75 | MAPK14 (0.34) | RETKDR | |
| SCHEMBL12650126 | 0.75 | HCAR2 (0.35) | CHRNB4CHRNA3 | |
| SCHEMBL1013121 | 0.73 | MEN1 (0.31) | — | |
| SCHEMBL23966693 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL9892872 | 0.73 | BRAF (0.34) | CHRNA1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25912648 | 0.73 | KDR (0.36) | CHRNA1CHRNB4CHRNA3CHRNA7KDR | |
| SCHEMBL23975356 | 0.72 | EGFR (0.36) | RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851092-B2 | Pyridine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |
| US-20200039974-A1 | PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039974-A1 | PYRIDINE COMPOUND | RET, ROS1, ABL1 | CHRNA1 3833/4885CHRNB4 4009/4885CHRNA3 4028/4885 |
| US-10851092-B2 | Pyridine compound | RET, ROS1, ABL1 | CHRNA1 3833/4885CHRNB4 4009/4885CHRNA3 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.