Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21674426 | 0.85 | IDO1 (0.34) | LPLLIPGP4HBBACE1IDO1 | |
| SCHEMBL16721591 | 0.82 | ROCK1 (0.35) | LPLLIPGP4HBIDO1TDO2 | |
| SCHEMBL23734063 | 0.82 | BACE1 (0.32) | LPLLIPGBACE1ROCK1 | |
| SCHEMBL16721589 | 0.82 | ROCK1 (0.35) | LPLLIPGP4HBIDO1TDO2 | |
| SCHEMBL594703 | 0.76 | LPL (0.36) | LPLLIPGIRAK4IDO1TDO2 | |
| SCHEMBL16123165 | 0.76 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL14158630 | 0.74 | LPL (0.37) | LPLLIPGIRAK4BACE1ROCK1 | |
| SCHEMBL12045687 | 0.73 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL19906344 | 0.71 | LPL (0.42) | LPLLIPGIRAK4IDO1TDO2 | |
| SCHEMBL12077094 | 0.69 | NPC1 (0.34) | LPLLIPGP4HBBACE1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |