Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 4/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21674425 | 0.85 | LPL (0.35) | IDO1TDO2LPLLIPGBACE1 | |
| SCHEMBL16721591 | 0.80 | ROCK1 (0.35) | IDO1TDO2LPLLIPGROCK1 | |
| SCHEMBL16721589 | 0.80 | ROCK1 (0.35) | IDO1TDO2LPLLIPGROCK1 | |
| SCHEMBL23734063 | 0.78 | BACE1 (0.32) | LPLLIPGBACE1ROCK1 | |
| SCHEMBL16123165 | 0.72 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL594703 | 0.69 | LPL (0.36) | IDO1TDO2LPLLIPGROCK1 | |
| SCHEMBL12045687 | 0.69 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL4495894 | 0.68 | ALDH1A1 (0.39) | IDO1TDO2LPLLIPGROCK1 | |
| SCHEMBL12077094 | 0.68 | NPC1 (0.34) | IDO1TDO2LPLLIPGBACE1 | |
| SCHEMBL12077092 | 0.68 | NPC1 (0.34) | IDO1TDO2LPLLIPGBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |