Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | LPL | P06858 | 4/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21674425 | 0.82 | LPL (0.35) | BACE1LPLLIPGROCK1 | |
| SCHEMBL16721591 | 0.79 | ROCK1 (0.35) | LPLLIPGROCK1 | |
| SCHEMBL16721589 | 0.79 | ROCK1 (0.35) | LPLLIPGROCK1 | |
| SCHEMBL21674426 | 0.78 | IDO1 (0.34) | BACE1LPLLIPGROCK1 | |
| SCHEMBL23734035 | 0.71 | GAA (0.40) | — | |
| SCHEMBL16123165 | 0.71 | LPL (0.36) | LPLLIPG | |
| SCHEMBL12045687 | 0.69 | LPL (0.36) | LPLLIPG | |
| SCHEMBL594703 | 0.69 | LPL (0.36) | LPLLIPGROCK1 | |
| SCHEMBL21532002 | 0.69 | BRD4 (0.46) | LPLLIPG | |
| SCHEMBL23084650 | 0.66 | LPL (0.39) | BACE1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084831-B1 | Benzopiperazine compositions as BET bromodomain inhibitors | FORMA THERAPEUTICS, INC. (US) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084831-B1 | Benzopiperazine compositions as BET bromodomain inhibitors | BRD4, BRPF3, BRD7 | BACE1 739/4885LPL 1376/4885LIPG 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.