Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 6/20 | 0.42 |
| ▸ | FEN1 | P39748 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21648942 | 0.89 | ALDH1A1 (0.36) | ALOX5APFEN1FFAR1FFAR4ALDH1A1 | |
| SCHEMBL9287992 | 0.77 | ALOX5AP (0.50) | ALOX5APFEN1FFAR1FFAR4MAPT | |
| SCHEMBL24940635 | 0.77 | ALDH1A1 (0.35) | ALOX5APFEN1ALDH1A1MAPTPOLB | |
| SCHEMBL2947210 | 0.75 | CYP11B1 (0.51) | ALOX5APFEN1TRPA1 | |
| SCHEMBL24940678 | 0.74 | ALDH1A1 (0.33) | FFAR1FFAR4ALDH1A1MAPTPOLB | |
| SCHEMBL18626170 | 0.74 | CYP11B1 (0.41) | ALDH1A1 | |
| SCHEMBL21675442 | 0.73 | BCL2 (0.40) | ALDH1A1MAPTPOLB | |
| SCHEMBL23347204 | 0.73 | ALOX5AP (0.56) | ALOX5APFEN1FFAR1FFAR4PDE3B | |
| SCHEMBL18626148 | 0.73 | CYP11B1 (0.44) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL11673411 | 0.72 | GRM5 (0.49) | ALOX5APFEN1FFAR1FFAR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3599266-B1 | LIQUID-CRYSTAL LENS | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| EP-3599266-A1 | LIQUID-CRYSTAL LENS | Merck Patent GmbH (DE) | 2020-01-29 | — | — | EP | disclosed |