Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.50 |
| ▸ | FEN1 | P39748 | 5/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23347204 | 0.83 | ALOX5AP (0.56) | ALOX5APFEN1TRPA1PDE3BPDE3A | |
| SCHEMBL11673411 | 0.82 | GRM5 (0.49) | ALOX5APFEN1TRPA1PDE3BPDE3A | |
| SCHEMBL17840122 | 0.79 | FEN1 (0.42) | ALOX5APFEN1CHRM2CHRM1CHRM3 | |
| SCHEMBL2395669 | 0.78 | ATR (0.39) | ALOX5APFEN1MAPTCHRM2CHRM1 | |
| SCHEMBL23075670 | 0.78 | ALDH1A1 (0.41) | ALOX5APFEN1PDE3BPDE3APTPN5 | |
| SCHEMBL2948017 | 0.78 | ALOX5AP (0.54) | ALOX5APFEN1TRPA1PDE3BPDE3A | |
| SCHEMBL21675486 | 0.77 | ALOX5AP (0.42) | ALOX5APFEN1TRPA1PDE3BPDE3A | |
| SCHEMBL2132813 | 0.77 | FEN1 (0.41) | ALOX5APFEN1CHRM2CHRM1CHRM3 | |
| SCHEMBL2950123 | 0.76 | ALOX5AP (0.50) | ALOX5APFEN1TRPA1PDE3BPDE3A | |
| SCHEMBL2949321 | 0.76 | ALOX5AP (0.53) | ALOX5APFEN1TRPA1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | ALOX5AP 1427/4885FEN1 4404/4885TRPA1 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.