Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SAT1 | P21673 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23131363 | 0.92 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL273581 | 0.82 | — | — | |
| SCHEMBL6019205 | 0.82 | SAT1 (0.39) | SIGMAR1TDP1L3MBTL1SAT1 | |
| SCHEMBL13165399 | 0.82 | SAT1 (0.39) | SIGMAR1TDP1L3MBTL1SAT1 | |
| SCHEMBL21675732 | 0.81 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL14416207 | 0.80 | NCF1 (0.42) | SIGMAR1TDP1L3MBTL1SAT1 | |
| SCHEMBL8888333 | 0.80 | NCF1 (0.42) | SIGMAR1TDP1L3MBTL1SAT1 | |
| Hydrochloric Acid SCHEMBL1165197 | 0.79 | — | — | |
| SCHEMBL11750040 | 0.79 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL25365 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3693022-A2 | COX-2-TARGETING, PLATINUM-CONTAINING CONJUGATES AND THEIR USE IN THE TREATMENT OF TUMORS AND CANCERS | Reiley Pharmaceuticals, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-3242688-B1 | COX-2-TARGETING, PLATINUM-CONTAINING CONJUGATES AND THEIR USE IN THE TREATMENT OF TUMORS AND CANCERS | REILEY PHARMACEUTICALS INC (US) | 2020-01-29 | — | — | EP | disclosed |