SCHEMBL21676065

SCHEMBL21676065

c1ccc(-c2ccc(-n3c4c5ccccc5ccc4c4ccc5c(c6ccccc6n5-c5ccc6c7c(cccc57)-c5ccccc5-6)c43)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.36
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21675966 0.94 L3MBTL1 (0.35)
SCHEMBL21676054 0.93 PDE6D (0.36) PDE6DMAPK14
SCHEMBL21676082 0.92 PDE10A (0.32) PDE6D
SCHEMBL21676147 0.90 PDE6D (0.36) PDE6DMAPK14
SCHEMBL21676066 0.89 L3MBTL1 (0.33)
SCHEMBL19213826 0.89 PDE6D (0.35) PDE6D
SCHEMBL21676077 0.88 ALDH1A1 (0.33)
SCHEMBL19213824 0.88 PDE6D (0.36) PDE6D
SCHEMBL21676084 0.87 L3MBTL1 (0.36) PDE6DMAPK14
SCHEMBL21676080 0.87 TDP1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020026133-A1 POLYCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-06 WO disclosed