SCHEMBL21676147

SCHEMBL21676147

c1ccc(-c2ccc(-n3c4ccccc4c4ccc5c(c6c7ccccc7ccc6n5-c5ccc6c7c(cccc57)-c5ccccc5-6)c43)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.36
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21676182 0.94 L3MBTL1 (0.38) KDM4EATML3MBTL1
SCHEMBL21676054 0.93 PDE6D (0.36) PDE6DKDM4EATML3MBTL1MAPK14
SCHEMBL21676154 0.92 PDE10A (0.32) PDE6DKDM4EATML3MBTL1
SCHEMBL21676065 0.90 PDE6D (0.36) PDE6DMAPK14
SCHEMBL19213826 0.89 PDE6D (0.35) PDE6DKDM4EATML3MBTL1
SCHEMBL21676156 0.88 ALDH1A1 (0.33) L3MBTL1
SCHEMBL21676164 0.88 TDP1 (0.36) ATML3MBTL1
SCHEMBL21676176 0.87 L3MBTL1 (0.39) PDE6DKDM4EATML3MBTL1MAPK14
SCHEMBL21676188 0.87 L3MBTL1 (0.40) KDM4EATML3MBTL1
SCHEMBL21676037 0.86 L3MBTL1 (0.36) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020026133-A1 POLYCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-06 WO disclosed