Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | WNT1 | P04628 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409785 | 0.90 | DRD4 (0.56) | DRD2DRD4WNT1GSK3BDYRK1A | |
| SCHEMBL17450652 | 0.86 | RAB9A (0.57) | KDM4EWNT1GSK3BDYRK1ASMN1; SMN2 | |
| SCHEMBL17450650 | 0.85 | RAB9A (0.56) | KDM4EWNT1GSK3BDYRK1AMAPT | |
| SCHEMBL17409783 | 0.85 | WNT1 (0.57) | KDM4EDRD2DRD4WNT1GSK3B | |
| SCHEMBL17409789 | 0.85 | DRD4 (0.51) | DRD2DRD4WNT1GSK3BDYRK1A | |
| SCHEMBL17450648 | 0.84 | ALDH1A1 (0.60) | KDM4EWNT1GSK3BDYRK1AMAPT | |
| SCHEMBL17403523 | 0.84 | WNT1 (0.53) | KDM4EWNT1GSK3BDYRK1ASMN1; SMN2 | |
| SCHEMBL15743960 | 0.83 | TSHR (0.72) | WNT1GSK3BDYRK1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21676988 | 0.83 | RAB9A (0.53) | DRD2DRD4SMN1; SMN2MAPTRAB9A | |
| SCHEMBL18998184 | 0.83 | RAB9A (0.53) | DRD2DRD4SMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319602-B1 | FUSED QUINOLINE COMPOUNDS AS PI3K/MTOR INHIBITORS | ADVENCHEN PHARMACEUTICALS LLC (US) | 2020-02-05 | — | — | EP | disclosed |