Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864161 | 0.90 | PRNP (0.45) | P2RX7NR1H2NR1H3CYP2D6MAOA | |
| SCHEMBL2872898 | 0.88 | NR1H2 (0.48) | P2RX7NR1H2NR1H3LMNACYP2D6 | |
| SCHEMBL28410705 | 0.86 | P2RX7 (0.45) | P2RX7NR1H2NR1H3CYP2D6MAOA | |
| SCHEMBL27967798 | 0.85 | ADORA2A (0.45) | ALDH1A1LMNAHPGDCYP2D6MAOA | |
| SCHEMBL27967875 | 0.84 | MEN1 (0.42) | P2RX7NR1H2NR1H3LMNACYP2D6 | |
| SCHEMBL27967693 | 0.83 | NUDT1 (0.41) | P2RX7NR1H2NR1H3CYP2D6MAOA | |
| SCHEMBL28812708 | 0.83 | P2RX7 (0.40) | P2RX7LMNACYP2D6MAOAMAPK1 | |
| SCHEMBL26111589 | 0.82 | HTR6 (0.39) | P2RX7NR1H2NR1H3CYP2D6MAOA | |
| SCHEMBL2867291 | 0.82 | KDM4E (0.48) | P2RX7NR1H2NR1H3LMNACYP2D6 | |
| SCHEMBL28397206 | 0.81 | NUDT1 (0.38) | P2RX7NR1H2NR1H3CYP2D6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011144117-A | 4-(DICHLOROPHENYL)-2-(4-FLUOROBENZYL)-5-METHYLIMIDAZOLE COMPOUND | SHIKOKU CHEM CORP | 2011-07-28 | — | — | JP | disclosed |