SCHEMBL21679463

SCHEMBL21679463

CSc1ccc(C(=O)c2ccc(Sc3ccccc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.63
ALDH1A1 P00352 3/20 0.63
L3MBTL1 Q9Y468 3/20 0.50
LMNA P02545 2/20 0.50
PLK1 P53350 1/20 0.48
AKR1C3 P42330 1/20 0.47
AKR1C2 P52895 1/20 0.47
AKR1C1 Q04828 1/20 0.47
SRD5A2 P31213 2/20 0.47
ATM Q13315 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
PDE4A P27815 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
PDE4B Q07343 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28304765 0.96 HPGD (0.58) HPGDALDH1A1L3MBTL1LMNAPLK1
SCHEMBL2149065 0.90 ALDH1A1 (0.61) HPGDALDH1A1L3MBTL1LMNAPLK1
SCHEMBL3282737 0.90 HPGD (0.69) HPGDALDH1A1L3MBTL1LMNASRD5A2
SCHEMBL385623 0.88 ALDH1A1 (0.67) HPGDALDH1A1L3MBTL1LMNASRD5A2
SCHEMBL21506865 0.88 ALDH1A1 (0.67) HPGDALDH1A1L3MBTL1LMNASRD5A2
SCHEMBL17828245 0.86 ALDH1A1 (0.67) HPGDALDH1A1L3MBTL1LMNASRD5A2
SCHEMBL17828242 0.86 ALDH1A1 (0.67) HPGDALDH1A1L3MBTL1LMNASRD5A2
SCHEMBL6787662 0.86 ALDH1A1 (0.67) HPGDALDH1A1L3MBTL1LMNASRD5A2
SCHEMBL6182687 0.85 PLK1 (0.61) HPGDALDH1A1L3MBTL1LMNAPLK1
SCHEMBL12256962 0.85 HPGD (0.89) HPGDALDH1A1L3MBTL1LMNASRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843853-B Composition and method for manufacturing device using the same 东洋合成工业株式会社 2022-09-20 CN disclosed
US-11142495-B2 Composition and method for manufacturing device using same TOYO GOSEI CO., LTD. (JP) 2021-10-12 US disclosed
US-11142495-B2 Composition and method for manufacturing device using same TOYO GOSEI CO., LTD. (JP) 2021-10-12 US disclosed
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME TOYO GOSEI CO., LTD. (JP) 2020-02-13 US disclosed
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME TOYO GOSEI CO., LTD. (JP) 2020-02-13 US disclosed
CN-109843853-A The manufacturing method of composition and the equipment using the composition 东洋合成工业株式会社 2019-06-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME LBR, LMTK2, MMS19 HPGD 3196/4885ALDH1A1 4785/4885L3MBTL1 2876/4885
US-11142495-B2 Composition and method for manufacturing device using same LBR, LMTK2, MMS19 HPGD 3196/4885ALDH1A1 4785/4885L3MBTL1 2876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.