Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31472599 | 0.93 | HAO1 (0.58) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL733870 | 0.91 | ALDH1A1 (0.70) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL10870869 | 0.91 | HPGD (0.61) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL7588971 | 0.91 | LMNA (0.65) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL2149065 | 0.91 | ALDH1A1 (0.61) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL24177551 | 0.89 | PLK1 (0.52) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL7808792 | 0.89 | AKR1C3 (0.58) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL7811075 | 0.89 | LMNA (0.55) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL15006707 | 0.89 | PLK1 (0.52) | PLK1HPGDNFKB1CYP1A2CYP3A4 | |
| SCHEMBL4030308 | 0.89 | LTA4H (0.53) | PLK1HPGDNFKB1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-213021053-U | Be used for producing condenser to methylthio propiophenone | 无极县腾益利化工有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-104093709-B | It is used as the imidazole derivative of aldosterone synthase inhibitors | 霍夫曼-拉罗奇有限公司 | 2017-09-22 | — | — | CN | claimed |
| US-4054682-A | COATINGS, PRINTING INKS | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-18 | — | — | US | claimed |
| EP-4748864-A1 | POLYMERIZATION INITIATOR OR PHOTOSENSITIZER, POLYMERIZATION INITIATION COMPOSITION, AND METHOD FOR PRODUCING RESIN | Miyoshi Oil & Fat Co., Ltd. (JP) | 2026-05-27 | — | — | EP | disclosed |
| US-20250197594-A1 | POLYETHER ETHER KETONE DECOMPOSITION METHOD AND NOVEL SUBSTANCE MADE BY USING DECOMPOSITION PRODUCT OBTAINED BY THIS DECOMPOSITION METHOD AS RAW MATERIAL | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2025-06-19 | — | — | US | disclosed |
| WO-2025063284-A1 | POLYMERIZATION INITIATOR OR PHOTOSENSITIZER, POLYMERIZATION INITIATION COMPOSITION, AND METHOD FOR PRODUCING RESIN | ミヨシ油脂株式会社 | 2025-03-27 | — | — | WO | disclosed |
| EP-4501908-A1 | POLYETHER ETHER KETONE DECOMPOSITION METHOD AND NOVEL SUBSTANCE USING STARTING MATERIAL THAT IS DECOMPOSITION PRODUCT OBTAINED BY THIS DECOMPOSITION METHOD | National Institute Of Advanced Industrial Science and Technology (JP) | 2025-02-05 | — | — | EP | disclosed |
| CN-114901468-B | Laminate, method for producing same, and exterior material for automobile | 三菱化学株式会社 | 2024-04-30 | — | — | CN | disclosed |
| WO-2023190767-A1 | POLYETHER ETHER KETONE DECOMPOSITION METHOD AND NOVEL SUBSTANCE USING STARTING MATERIAL THAT IS DECOMPOSITION PRODUCT OBTAINED BY THIS DECOMPOSITION METHOD | 国立研究開発法人産業技術総合研究所 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023190767-A1 | POLYETHER ETHER KETONE DECOMPOSITION METHOD AND NOVEL SUBSTANCE USING STARTING MATERIAL THAT IS DECOMPOSITION PRODUCT OBTAINED BY THIS DECOMPOSITION METHOD | 国立研究開発法人産業技術総合研究所 | 2023-10-05 | — | — | WO | disclosed |
| CN-106316898-B | The synthetic method of Florfenicol | 湖北美天生物科技股份有限公司 | 2018-06-01 | — | — | CN | disclosed |
| US-20040162314-A1 | Substituted 8-arylquinolune pde4 inhibitors | MERCK FROSST CANADA LTD. (CA) | 2004-08-19 | — | — | US | disclosed |
| EP-1404330-A1 | SUBSTITUTED 8-ARYLQUINOLINE PDE4 INHIBITORS | Merck Frosst Canada & Co. (CA) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003002118-A1 | SUBSTITUTED 8-ARYLQUINOLINE PDE4 INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2003-01-09 | — | — | WO | disclosed |
| EP-0508999-A1 | PHARMACEUTICALLY ACTIVE NORMONYL COMPOUNDS | Beecham Group p.l.c. (GB) | 1992-10-21 | — | — | EP | disclosed |
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| WO-1991009855-A1 | PHARMACEUTICALLY ACTIVE NORMONYL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1991-07-11 | — | — | WO | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4054682-A | COATINGS, PRINTING INKS | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162314-A1 | Substituted 8-arylquinolune pde4 inhibitors | PDE12, PDE4A, PDE4B | PLK1 3734/4885HPGD 821/4885NFKB1 671/4885 |
| US-20250197594-A1 | POLYETHER ETHER KETONE DECOMPOSITION METHOD AND NOVEL SUBSTANCE MADE BY USING DECOMPOSITION PRODUCT OBTAINED BY THIS DECOMPOSITION METHOD AS RAW MATERIAL | TST, MPST, ALKBH3 | PLK1 4335/4885HPGD 2748/4885NFKB1 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.