SCHEMBL21679520

SCHEMBL21679520

O=Cc1c(Cl)ccc2cc(Br)ccc12

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 0.65
ALDH1A1 P00352 6/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
NCEH1 Q6PIU2 2/20 0.39
CYP2A6 P11509 4/20 0.39
KDM4E B2RXH2 3/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6820167 0.81 TDP1 (0.44) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL1414921 0.79 ERN1 (1.00) ERN1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL6819375 0.78 ERN1 (0.59) ERN1ALDH1A1MEN1KMT2ANCEH1
SCHEMBL24215332 0.75 CYP2A6 (0.50) ERN1ALDH1A1MEN1KMT2ANCEH1
SCHEMBL38663463 0.75 ERN1 (0.59) ERN1ALDH1A1MEN1KMT2ACYP2A6
SCHEMBL3008338 0.75 ERN1 (0.59) ERN1ALDH1A1MEN1KMT2ANCEH1
SCHEMBL15577736 0.75 ERN1 (0.51) ERN1ALDH1A1NCEH1CYP2A6
SCHEMBL28948948 0.75 CYP1A2 (0.43) ERN1ALDH1A1CYP2A6KDM4EMAPT
SCHEMBL30067006 0.75 ERN1 (0.59) ERN1ALDH1A1MEN1KMT2ANCEH1
SCHEMBL1246034 0.73 ERN1 (0.60) ERN1ALDH1A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843853-B Composition and method for manufacturing device using the same 东洋合成工业株式会社 2022-09-20 CN disclosed
US-11142495-B2 Composition and method for manufacturing device using same TOYO GOSEI CO., LTD. (JP) 2021-10-12 US disclosed
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME TOYO GOSEI CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME LBR, LMTK2, MMS19 ERN1 915/4885ALDH1A1 4785/4885MEN1 3312/4885
US-11142495-B2 Composition and method for manufacturing device using same LBR, LMTK2, MMS19 ERN1 915/4885ALDH1A1 4785/4885MEN1 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.