Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3008338 | 1.00 | ERN1 (0.59) | ERN1POLBRXFP1L3MBTL1KDM4E | |
| SCHEMBL5755021 | 0.93 | ERN1 (0.52) | ERN1POLBRXFP1L3MBTL1KDM4E | |
| SCHEMBL5755025 | 0.93 | ERN1 (0.52) | ERN1POLBRXFP1L3MBTL1KDM4E | |
| SCHEMBL5755022 | 0.90 | ERN1 (0.54) | ERN1POLBRXFP1L3MBTL1KDM4E | |
| SCHEMBL6952319 | 0.89 | ERN1 (0.49) | ERN1POLBRXFP1L3MBTL1KDM4E | |
| SCHEMBL15414637 | 0.89 | ERN1 (0.46) | ERN1POLBRXFP1L3MBTL1KDM4E | |
| SCHEMBL5752881 | 0.84 | RXFP1 (0.50) | ERN1POLBRXFP1L3MBTL1KDM4E | |
| SCHEMBL30066982 | 0.82 | MTNR1A (0.51) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14047249 | 0.82 | ACHE (0.46) | ERN1L3MBTL1KDM4ELMNAMAPT | |
| SCHEMBL10388887 | 0.82 | MTNR1A (0.51) | ERN1MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022233824-A1 | NAPHTHALENE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | INSTITUT CURIE (FR) | 2022-11-10 | — | — | WO | disclosed |