Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21681910 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL28554700 | 0.71 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL21681903 | 0.71 | LMNA (0.44) | ALDH1A1LMNAGAAKMT2ARECQL | |
| SCHEMBL25180681 | 0.68 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL21681901 | 0.67 | BRD4 (0.36) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL7498474 | 0.63 | LMNA (0.42) | ALDH1A1LMNAGAAKMT2ARECQL | |
| SCHEMBL17357927 | 0.63 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAKMT2ARECQL | |
| SCHEMBL633228 | 0.62 | LMNA (0.54) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL17357984 | 0.62 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL30366666 | 0.62 | ALDH1A1 (0.46) | ALDH1A1LMNAGAAKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238176-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-08-05 | — | — | US | disclosed |
| US-20210238176-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-08-05 | — | — | US | disclosed |
| EP-3833663-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-06-16 | — | — | EP | disclosed |
| CN-112585137-A | Pesticidally active bicyclic heteroaromatic compounds | 先正达农作物保护股份公司 | 2021-03-30 | — | — | CN | disclosed |
| WO-2020030503-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030503-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238176-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, CYP1B1 | ALDH1A1 659/4885KDM4E 3449/4885LMNA 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.