Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 12/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 2/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21772261 | 0.89 | LCK (0.61) | LCKSIRT2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21682161 | 0.78 | SMN1; SMN2 (0.64) | LCKKDM4EALDH1A1SMN1; SMN2SCD | |
| SCHEMBL6058291 | 0.78 | HTT (0.61) | LCKALDH1A1SMN1; SMN2SCDNPC1 | |
| SCHEMBL21709937 | 0.78 | NPC1 (0.70) | LCKKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL21682154 | 0.78 | SCD (0.70) | LCKALDH1A1SMN1; SMN2SCDNPC1 | |
| SCHEMBL31398557 | 0.74 | HSD17B10 (0.67) | SMN1; SMN2SCDNPC1RAB9AHTT | |
| SCHEMBL29532955 | 0.74 | CASP3 (0.65) | ALDH1A1SMN1; SMN2SCDNPC1RAB9A | |
| SCHEMBL17251803 | 0.74 | CASP3 (0.65) | ALDH1A1SMN1; SMN2SCDNPC1RAB9A | |
| SCHEMBL6057728 | 0.73 | LCK (0.82) | LCK | |
| SCHEMBL21681925 | 0.73 | RAB9A (0.68) | LCKKDM4EALDH1A1SMN1; SMN2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033782-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-1\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-13 | — | — | WO | claimed |