Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682807 | 1.00 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21682808 | 1.00 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1789373 | 0.79 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2413101 | 0.79 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7138872 | 0.79 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL357768 | 0.78 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14619869 | 0.73 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Methacrylic Acid SCHEMBL11062934 | 0.73 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL43207 | 0.73 | — | — | |
| SCHEMBL12714083 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210393677-A1 | COMPOUNDS FOR MODULATION AND AS FUNCTIONAL REPLACEMENT OF ALPHAKETOGLUTARIC ACID (2OG)-DEPENDENT OXYGENASES | HOMANN THOMAS (DE) | 2021-12-23 | — | — | US | disclosed |
| CN-113164617-A | Compounds for modulating and as a functional replacement for alpha-ketoglutarate (2OG) dependent oxygenase | 托马斯·梅尔希奥·霍曼 | 2021-07-23 | — | — | CN | disclosed |
| EP-3762038-A1 | COMPOUNDS FOR MODULATION AND AS FUNCTIONAL REPLACEMENT OF ALPHA-KETOGLUTARIC ACID (2OG)-DEPENDENT OXYGENASES | Homann, Thomas Melchior (DE) | 2021-01-13 | — | — | EP | disclosed |
| WO-2020030826-A9 | COMPOUNDS FOR MODULATION AND AS FUNCTIONAL REPLACEMENT OF ALPHA-KETOGLUTARIC ACID (2OG)-DEPENDENT OXYGENASES | HOMANN THOMAS MELCHIOR (DE) | 2020-04-09 | — | — | WO | disclosed |
| WO-2020030826-A1 | COMPOUNDS FOR MODULATION AND AS FUNCTIONAL REPLACEMENT OF ALPHA-KETOGLUTARIC ACID (2OG)-DEPENDENT OXYGENASES | HOMANN THOMAS MELCHIOR (DE) | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210393677-A1 | COMPOUNDS FOR MODULATION AND AS FUNCTIONAL REPLACEMENT OF ALPHAKETOGLUTARIC ACID (2OG)-DEPENDENT OXYGENASES | OGDH, HOGA1, GCDH | GABRP 1559/4885GABRD 1921/4885GABRA1 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.