Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18887323 | 0.88 | LMNA (0.32) | LMNATP53POLBMAPTBTK | |
| SCHEMBL2167838 | 0.85 | MAPT (0.35) | LMNATP53POLBMAPTBTK | |
| SCHEMBL2168910 | 0.83 | SMN1; SMN2 (0.42) | LMNATP53POLBMAPTSMN1; SMN2 | |
| SCHEMBL2167362 | 0.82 | HRH3 (0.41) | LMNATP53POLBMAPTSMN1; SMN2 | |
| SCHEMBL2167567 | 0.81 | SMN1; SMN2 (0.36) | LMNATP53POLBMAPTBTK | |
| SCHEMBL2169831 | 0.80 | HPGD (0.40) | LMNATP53POLBMAPTSMN1; SMN2 | |
| SCHEMBL2171193 | 0.80 | HPGD (0.39) | LMNATP53POLBMAPTSMN1; SMN2 | |
| SCHEMBL2168080 | 0.80 | POLB (0.36) | LMNATP53POLBMAPTKDM5A | |
| SCHEMBL2170222 | 0.79 | MAPT (0.39) | LMNATP53POLBMAPTSMN1; SMN2 | |
| SCHEMBL2169211 | 0.79 | ITK (0.38) | LMNATP53POLBMAPTABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |