Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184240 | 0.89 | HRH3 (0.44) | HRH3HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2168910 | 0.88 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL18887347 | 0.88 | HRH3 (0.39) | HRH3HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2167838 | 0.85 | MAPT (0.35) | SMN1; SMN2MEN1KMT2ATP53LMNA | |
| SCHEMBL2167567 | 0.85 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL2167566 | 0.84 | ADRA1A (0.37) | ALDH1A1SMN1; SMN2HPGDHPGDSNPC1 | |
| SCHEMBL2171166 | 0.83 | MEN1 (0.44) | HRH3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2169831 | 0.82 | HPGD (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL2171193 | 0.82 | HPGD (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL2168355 | 0.82 | LMNA (0.33) | SMN1; SMN2TP53LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |