SCHEMBL2168523

SCHEMBL2168523

[CH]c1ccc([Si](CC)(CC)CC)cc1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.45
NR1H3 Q13133 2/20 0.45
ESR1 P03372 2/20 0.37
AR P10275 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7056361 0.85 NR1H2 (0.54) NR1H2NR1H3ESR1ARESR2
SCHEMBL988371 0.74 ACHE (0.47) NR1H2NR1H3ESR1ARESR2
SCHEMBL27568459 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ARESR2
SCHEMBL27980976 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ARESR2
SCHEMBL2114379 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ESR2
SCHEMBL23190380 0.72 NR1H2 (0.50) NR1H2NR1H3ESR1
SCHEMBL14437782 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ARESR2
SCHEMBL16537645 0.72 ESR1 (0.68) NR1H2NR1H3ESR1ARESR2
SCHEMBL9243328 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1
SCHEMBL988676 0.71 NR1H2 (0.43) NR1H2NR1H3ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
CN-109563189-B Method for supplying solid catalyst to solution polymerization reactor 埃克森美孚化学专利公司 2021-06-18 CN disclosed
CN-108794675-B Process for the preparation of ethylene propylene copolymers 埃克森美孚化学专利公司 2020-12-29 CN disclosed
CN-101018815-B Multiple catalyst and reactor system for olefin polymerization and polymers produced thereby EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-11-30 CN disclosed
CN-102439106-B Polyolefin adhesive compositions EXXONMOBIL CHEM PATENTS INC 2015-03-25 CN disclosed
EP-2528957-B1 COPOLYMERS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING THEM EXXONMOBIL CHEM PATENTS INC (US) 2014-10-22 EP disclosed
EP-2528957-A1 COPOLYMERS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING THEM ExxonMobil Chemical Patents Inc. (US) 2012-12-05 EP disclosed
WO-2011094057-A1 COPOLYMERS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING THEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-04 WO disclosed
US-20110184134-A1 Copolymers, Compositions Thereof, and Methods for Making Them EXXONMOBIL CHEMICAL PATENTS INC. 2011-07-28 US disclosed