SCHEMBL27980976

SCHEMBL27980976

[CH2]c1ccc([Si](CC)(CC)CC)cc1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.45
NR1H3 Q13133 2/20 0.45
ESR1 P03372 2/20 0.37
AR P10275 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7056361 0.85 NR1H2 (0.54) NR1H2NR1H3ESR1ARESR2
SCHEMBL988371 0.74 ACHE (0.47) NR1H2NR1H3ESR1ARESR2
SCHEMBL9243328 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1
SCHEMBL2168523 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ARESR2
SCHEMBL27568459 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ARESR2
SCHEMBL23190380 0.72 NR1H2 (0.50) NR1H2NR1H3ESR1
SCHEMBL16537645 0.72 ESR1 (0.68) NR1H2NR1H3ESR1ARESR2
SCHEMBL14437782 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ARESR2
SCHEMBL2114379 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ESR2
SCHEMBL2354943 0.72 ALDH1A1 (0.52) NR1H2NR1H3ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471244-B Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound ASAHI CHEMICAL CORP 2014-09-24 CN disclosed