Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13740768 | 0.83 | HPGD (0.62) | HPGDGAAL3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL29143516 | 0.82 | HPGD (0.55) | HPGDGAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL21686851 | 0.81 | CA12 (0.55) | HPGDGAAKMT2AMEN1LMNA | |
| SCHEMBL21686866 | 0.80 | HTT (0.49) | HPGDGAAKMT2AMEN1LMNA | |
| SCHEMBL21686864 | 0.79 | ALOX15 (0.47) | KMT2AMEN1LMNATSHRSMN1; SMN2 | |
| SCHEMBL15601951 | 0.77 | KEAP1 (0.50) | HPGDKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL21686847 | 0.77 | LMNA (0.51) | HPGDKMT2AMEN1LMNATSHR | |
| SCHEMBL13741560 | 0.76 | HPGD (0.66) | HPGDGAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL21686846 | 0.75 | CDK1 (0.53) | GAAKMT2ASMN1; SMN2MAPTTP53 | |
| SCHEMBL27183267 | 0.73 | HPGD (0.62) | HPGDGAAL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020020939-A1 | PYRIDOPYRIMIDINES AS HISTAMINE H4-RECEPTOR INHIBITORS | FAES FARMA, S.A. (ES) | 2020-01-30 | — | — | WO | disclosed |