SCHEMBL21687665

SCHEMBL21687665

N#Cc1ccc2c(c1)c1cc(C#N)ccc1n2-c1ccc(-c2c(C#N)cccc2[Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARG P13631 1/20 0.33
USP14 P54578 1/20 0.33
TDP2 O95551 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
FASN P49327 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21688016 0.97 KDM4E (0.34) RARGUSP14TDP2ALDH1A1LMNA
SCHEMBL21687487 0.91 LMNA (0.35) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21687990 0.89 ALDH1A1 (0.34) RARGUSP14TDP2ALDH1A1LMNA
SCHEMBL21687689 0.89 KDM4E (0.34) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21688070 0.88 PTGER4 (0.33) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL21688077 0.88 KDM4E (0.41) ALDH1A1LMNAHPGDMAPK1SMN1; SMN2
SCHEMBL21687993 0.87 SMN1; SMN2 (0.34) RARGTDP2ALDH1A1LMNAHPGD
SCHEMBL21687873 0.87 CYP1A2 (0.32) ALDH1A1LMNAMAPK1SMN1; SMN2MEN1
SCHEMBL21687531 0.86 KDM4E (0.34) RARGALDH1A1LMNAHPGDMAPK1
SCHEMBL21688067 0.86 PTGER4 (0.33) ALDH1A1LMNASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-14 US disclosed
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND CRY1, CCNL2, CCNE2 RARG 1498/4885USP14 3552/4885TDP2 4123/4885
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound CRY1, CCNL2, CCNE2 RARG 1498/4885USP14 3552/4885TDP2 4123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.