SCHEMBL21687685

SCHEMBL21687685

N#Cc1ccc2c(c1)c1ccccc1n2-c1cc(-c2ccc(C#N)c([Si](c3ccccc3)(c3ccccc3)c3ccccc3)c2)ccc1C#N

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.34
RORC P51449 3/20 0.32
HRH1 P35367 1/20 0.31
HTR6 P50406 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21687472 0.94 PTGER4 (0.34) PTGER4RORCHRH1HTR6KDM4E
SCHEMBL21687663 0.93 PTGER4 (0.33) PTGER4RORCHRH1HTR6KDM4E
SCHEMBL21687739 0.92 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL21688173 0.92 PTGER4 (0.33) PTGER4
SCHEMBL21687483 0.92 KDM4E (0.35) PTGER4KDM4EATML3MBTL1ALDH1A1
SCHEMBL21687900 0.91 PTGER4 (0.35) PTGER4RORCHRH1HTR6KDM4E
SCHEMBL21688174 0.90 PTGER4 (0.33) PTGER4RORC
SCHEMBL21687496 0.90 ALDH1A1 (0.36) PTGER4KDM4EATML3MBTL1ALDH1A1
SCHEMBL21688105 0.90 PTGER4 (0.33) PTGER4RORC
SCHEMBL21688022 0.89 PTGER4 (0.34) PTGER4RORCHRH1HTR6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-14 US disclosed
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND CRY1, CCNL2, CCNE2 PTGER4 553/4885RORC 1486/4885HRH1 1158/4885
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound CRY1, CCNL2, CCNE2 PTGER4 553/4885RORC 1486/4885HRH1 1158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.