SCHEMBL21687900

SCHEMBL21687900

N#Cc1ccc2c(c1)c1ccccc1n2-c1cc(-c2ccc([Si](c3ccccc3)(c3ccccc3)c3ccccc3)cc2)ccc1C#N

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.35
RORC P51449 3/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
HRH1 P35367 1/20 0.32
HTR6 P50406 1/20 0.32
ATM Q13315 2/20 0.31
KDM4E B2RXH2 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 3/20 0.31
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ENPP3 O14638 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21687712 0.97 CYP11B1 (0.34) CYP11B1CYP11B2HRH1HTR6KDM4E
SCHEMBL21688022 0.94 PTGER4 (0.34) PTGER4RORCCYP11B1CYP11B2HRH1
SCHEMBL21687679 0.92 PTGER4 (0.35) PTGER4RORCCYP11B1CYP11B2HRH1
SCHEMBL21687623 0.92 CYP11B1 (0.37) CYP11B1CYP11B2ATMKDM4EL3MBTL1
SCHEMBL21687746 0.92 PTGER4 (0.33) PTGER4RORCCYP11B1CYP11B2GAA
SCHEMBL21687522 0.92 PTGER4 (0.33) PTGER4RORC
SCHEMBL21687685 0.91 PTGER4 (0.34) PTGER4RORCHRH1HTR6ATM
SCHEMBL21687663 0.90 PTGER4 (0.33) PTGER4RORCHRH1HTR6KDM4E
SCHEMBL21688095 0.90 FLT3 (0.33) PTGER4CYP11B1CYP11B2ATMKDM4E
SCHEMBL21116480 0.89 RORC (0.38) PTGER4RORCHRH1HTR6ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-14 US disclosed
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND CRY1, CCNL2, CCNE2 PTGER4 553/4885RORC 1486/4885CYP11B1 1222/4885
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound CRY1, CCNL2, CCNE2 PTGER4 553/4885RORC 1486/4885CYP11B1 1222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.