SCHEMBL21689652

SCHEMBL21689652

CC1(C)OB(c2ccc3c(c2)-c2ccccc2C32CCCCC2)OC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPL P06858 12/20 0.42
LIPG Q9Y5X9 12/20 0.42
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
ROCK1 Q13464 1/20 0.34
BACE1 P56817 1/20 0.34
P4HB P07237 1/20 0.33
PGR P06401 1/20 0.32
EGFR P00533 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31624922 0.99 LPL (0.43) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL17070766 0.92 LPL (0.42) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL21689732 0.91 LPL (0.35) LPLLIPGPRMT5WDR77BACE1
SCHEMBL31624712 0.90 LPL (0.43) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL26639956 0.88 LIPG (0.43) LPLLIPGPRMT5WDR77BACE1
SCHEMBL26639914 0.86 LIPG (0.43) LPLLIPGPRMT5WDR77BACE1
SCHEMBL30953162 0.85 LIPG (0.51) LPLLIPGPRMT5WDR77P4HB
SCHEMBL13227406 0.84 LPL (0.40) LPLLIPGPRMT5WDR77BACE1
SCHEMBL15895327 0.84 LPL (0.40) LPLLIPGPRMT5WDR77BACE1
SCHEMBL27192771 0.83 LIPG (0.43) LPLLIPGPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912672-B2 Organic compound and organic electroluminescent device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2024-02-27 US disclosed
US-11912672-B2 Organic compound and organic electroluminescent device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2024-02-27 US disclosed
US-20210253542-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN SOLUS CO., LTD. (KR) 2021-08-19 US disclosed
WO-2021034081-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 솔루스첨단소재 주식회사 2021-02-25 WO disclosed
WO-2020027463-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 2020-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253542-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME OR10J3, TRPA1, TRPM4 LPL 352/4885LIPG 630/4885PRMT5 4421/4885
US-11912672-B2 Organic compound and organic electroluminescent device using same OR10J3, TRPA1, TRPM4 LPL 352/4885LIPG 630/4885PRMT5 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.