Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453836 | 0.87 | AKR1C2 (0.59) | PTGS1AKR1C3AKR1C2SLC2A1MTNR1A | |
| SCHEMBL2169394 | 0.86 | AKR1C3 (0.44) | AKR1C3AKR1C2MTNR1AKDM4ECYP1A2 | |
| SCHEMBL2170286 | 0.86 | ALDH1A1 (0.41) | MTNR1AKDM4ENPC1LMNATP53 | |
| SCHEMBL9504259 | 0.86 | KDM4E (0.53) | PTGS1AKR1C3AKR1C2SLC2A1MTNR1A | |
| SCHEMBL2169163 | 0.84 | TSHR (0.43) | MTNR1AKDM4ERAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL17013394 | 0.82 | SLC2A1 (0.46) | PTGS1AKR1C3AKR1C2SLC2A1MTNR1A | |
| SCHEMBL2170323 | 0.81 | ALOX5 (0.50) | KDM4ECYP1A2NPC1MAOARAB9A | |
| SCHEMBL11377119 | 0.78 | MTNR1A (0.47) | SLC2A1MTNR1AMTNR1B | |
| SCHEMBL11294989 | 0.77 | SLC2A1 (0.42) | PTGS1AKR1C3AKR1C2SLC2A1MTNR1A | |
| SCHEMBL2171722 | 0.77 | SLC2A1 (0.42) | PTGS1AKR1C3AKR1C2SLC2A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096493-B2 | Preparation method of high-purity L-carnitine | CHANGZHOU MULTIPLE DIMENSION INSTITUTE OF INDUSTRY TECHNOLOGY CO., LTD. (CN) | 2015-08-04 | — | — | US | claimed |
| US-8709819-B2 | Preparation and its use of derivatization reagent for detecting L-carnitine or D-carnitine | GU SHUHUA (CN) | 2014-04-29 | — | — | US | claimed |
| EP-2348315-B1 | PREPARATION AND ITS USE OF DERIVATISATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | CHANGZHOU MULTIPLE DIMENSION INST OF INDUSTRY TECHNOLOGY CO LTD (CN) | 2013-12-18 | — | — | EP | claimed |
| EP-2360141-B1 | A PREPARATION METHOD OF HIGH-PURITY L-CARNITINE | CHANGZHOU MULTIPLE DIMENSION INST OF INDUSTRY TECHNOLOGY CO LTD (CN) | 2013-12-11 | — | — | EP | claimed |
| US-20110281293-A1 | PREPARATION AND ITS USE OF DERIVATIZATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | GU SHUHUA (CN) | 2011-11-17 | — | — | US | claimed |
| US-20110263897-A1 | PREPARATION METHOD OF HIGH-PURITY L-CARNITINE | CHANGZHOU MULTIPLE DIMENSION INSTITUTE OF INDUSTRY TECHNOLOGY CO., LTD. (CN) | 2011-10-27 | — | — | US | claimed |
| EP-2360141-A1 | A PREPARATION METHOD OF HIGH-PURITY L-CARNITINE | Changzhou Multiple Dimension Institute Of Industry Technology Co., Ltd. (CN) | 2011-08-24 | — | — | EP | claimed |
| EP-2348315-A1 | PREPARATION AND ITS USE OF DERIVATISATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | Changzhou Multiple Dimension Institute Of Industry Technology Co., Ltd. (CN) | 2011-07-27 | — | — | EP | claimed |
| US-9096493-B2 | Preparation method of high-purity L-carnitine | CHANGZHOU MULTIPLE DIMENSION INSTITUTE OF INDUSTRY TECHNOLOGY CO., LTD. (CN) | 2015-08-04 | — | — | US | disclosed |
| US-8709819-B2 | Preparation and its use of derivatization reagent for detecting L-carnitine or D-carnitine | GU SHUHUA (CN) | 2014-04-29 | — | — | US | disclosed |
| EP-2348315-B1 | PREPARATION AND ITS USE OF DERIVATISATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | CHANGZHOU MULTIPLE DIMENSION INST OF INDUSTRY TECHNOLOGY CO LTD (CN) | 2013-12-18 | — | — | EP | disclosed |
| EP-2360141-B1 | A PREPARATION METHOD OF HIGH-PURITY L-CARNITINE | CHANGZHOU MULTIPLE DIMENSION INST OF INDUSTRY TECHNOLOGY CO LTD (CN) | 2013-12-11 | — | — | EP | disclosed |
| US-20110281293-A1 | PREPARATION AND ITS USE OF DERIVATIZATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | GU SHUHUA (CN) | 2011-11-17 | — | — | US | disclosed |
| US-20110263897-A1 | PREPARATION METHOD OF HIGH-PURITY L-CARNITINE | CHANGZHOU MULTIPLE DIMENSION INSTITUTE OF INDUSTRY TECHNOLOGY CO., LTD. (CN) | 2011-10-27 | — | — | US | disclosed |
| US-4217352-A | ANTIARTHRITIC AGENT | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212976-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |
| US-4144342-A | ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4061759-A | ANTIINFLAMMATORY, ARTHRITIS | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4057637-A | RHEUMATOID ARTHRITIS | MERCK & CO., INC. (US) | 1977-11-08 | — | — | US | disclosed |
| US-3971797-A | ANTIARTHRITIC | MERCK & CO., INC. (US) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281293-A1 | PREPARATION AND ITS USE OF DERIVATIZATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | CRAT, CPT1B, SLC25A20 | PTGS1 4853/4885AKR1C3 1211/4885AKR1C2 876/4885 |
| US-20110263897-A1 | PREPARATION METHOD OF HIGH-PURITY L-CARNITINE | CPT2, CRAT, CPT1B | PTGS1 4593/4885AKR1C3 2619/4885AKR1C2 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.