Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 17/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1409521 | 0.89 | DUT (0.69) | DUTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL1409522 | 0.89 | DUT (0.69) | DUTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL1409351 | 0.81 | DUT (1.00) | DUT | |
| SCHEMBL1409353 | 0.81 | DUT (1.00) | DUT | |
| SCHEMBL12630195 | 0.78 | DUT (0.56) | DUT | |
| SCHEMBL21690325 | 0.77 | DUT (0.68) | DUT | |
| SCHEMBL21690993 | 0.77 | DUT (0.68) | DUT | |
| SCHEMBL22392894 | 0.76 | RIPK1 (0.52) | DUT | |
| SCHEMBL20361647 | 0.75 | DUT (0.68) | DUT | |
| SCHEMBL21325376 | 0.75 | DUT (0.68) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247984-B2 | Uracil containing compounds | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2022-02-15 | — | — | US | disclosed |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | UNG, DPYD, DUT | DUT 3/4885ALDH1A1 970/4885LMNA 1631/4885 |
| US-11247984-B2 | Uracil containing compounds | UNG, DPYD, DUT | DUT 3/4885ALDH1A1 970/4885LMNA 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.