SCHEMBL21691076

SCHEMBL21691076

Cc1cc2[nH]c(C=O)cc2o1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.40
SMYD3 Q9H7B4 3/20 0.38
NOS1 P29475 2/20 0.34
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
KMO O15229 1/20 0.32
NQO1 P15559 1/20 0.32
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA3 P42263 1/20 0.32
GRIA4 P48058 1/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31
PSMB8 P28062 1/20 0.31
KEAP1 Q14145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5040720 0.73 SMYD3 (0.40) CYP2A6SMYD3NOS1NOS3NOS2
SCHEMBL9996143 0.69 MAOB (0.49) CYP1A1CYP1A2CYP1B1
SCHEMBL3360077 0.68 DAO (0.46) SMYD3CYP1A2
SCHEMBL1244189 0.68 SMYD3 (0.54) SMYD3
SCHEMBL21691074 0.68 SMYD3 (0.30) SMYD3
SCHEMBL2406831 0.67 SMYD3 (0.53) SMYD3NOS1NOS3NOS2
SCHEMBL31373781 0.67 CYP2A6 (0.41) CYP2A6NOS1NOS3NOS2KMO
SCHEMBL29951448 0.66 CYP2A6 (0.37) CYP2A6GRIA1GRIA2GRIA3GRIA4
SCHEMBL1673129 0.64 NOS1 (0.37) SMYD3NOS1NOS3NOS2KMO
SCHEMBL22397020 0.64 CYP2A6 (0.52) CYP2A6GRIA1GRIA2GRIA3GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-10886479-B2 Photoelectric conversion element, optical sensor, imaging element, and compound FUJIFILM CORPORATION (JP) 2021-01-05 US disclosed
US-20200035933-A1 PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, IMAGING ELEMENT, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-01-30 US disclosed