Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483347 | 0.73 | ALOX15 (0.38) | SMN1; SMN2KDM4EMAPTALOX15GLA | |
| SCHEMBL15046540 | 0.70 | NOS1 (0.53) | NOS1NOS3NOS2CYP1A2LMNA | |
| SCHEMBL5040720 | 0.67 | SMYD3 (0.40) | NOS1NOS3NOS2NQO1SMYD3 | |
| SCHEMBL3360077 | 0.67 | DAO (0.46) | SMYD3TP53CYP1A2SMN1; SMN2PTGS1 | |
| SCHEMBL19153579 | 0.65 | CYP1A2 (0.41) | CYP1A2SMN1; SMN2MAPTATAD2BRD4 | |
| SCHEMBL2977301 | 0.65 | DAO (0.42) | POLB | |
| SCHEMBL19153109 | 0.64 | CYP1A2 (0.44) | CYP1A2KDM4EGAAMAPTATAD2 | |
| SCHEMBL21691076 | 0.64 | CYP2A6 (0.40) | NOS1NOS3NOS2NQO1SMYD3 | |
| SCHEMBL25911967 | 0.64 | CYP1A2 (0.37) | NOS1NOS3NOS2CYP1A2POLB | |
| SCHEMBL15473324 | 0.63 | NOS1 (0.45) | NOS1NOS3NOS2CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309356-B2 | Pseudocomplementary oligonucleotides for targeted gene therapy | YALE UNIVERSITY (US) | 2012-11-13 | — | — | US | disclosed |
| US-20110086905-A1 | Pseudocomplementary Oligonucleotides for Targeted Gene Therapy | YALE UNIVERSITY | 2011-04-14 | — | — | US | disclosed |