Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26274192 | 0.83 | TSHR (0.42) | TSHRAPPBRD4 | |
| SCHEMBL6847221 | 0.82 | TSHR (0.41) | TSHRAPPBRD4 | |
| SCHEMBL6848815 | 0.82 | TSHR (0.41) | TSHRAPPBRD4 | |
| SCHEMBL20048797 | 0.80 | TSHR (0.39) | TSHRAPPBRD4 | |
| Hydrochloric Acid SCHEMBL6841993 | 0.80 | TSHR (0.39) | TSHRAPPBRD4 | |
| SCHEMBL23240078 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6846381 | 0.80 | TSHR (0.39) | TSHRAPPBRD4 | |
| SCHEMBL20048796 | 0.80 | TSHR (0.39) | TSHRAPPBRD4NOS1 | |
| SCHEMBL25697637 | 0.74 | CA12 (0.45) | TSHRAPPCA12CA1CA2 | |
| SCHEMBL15085130 | 0.72 | ACHE (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802110-B2 | 2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase | Oxford Drug Design Limited (GB) | 2023-10-31 | — | — | US | disclosed |
| CN-110049970-B | 2-amino-N- (arylsulfinyl) -acetamide compounds as inhibitors of bacterial aminoacyl-TRNA synthase | 牛津药物设计有限公司 | 2023-04-11 | — | — | CN | disclosed |
| US-20200039929-A1 | 2-AMINO-N-(ARYLSULFINYL)-ACETAMIDE COMPOUNDS AS INHIBITORS OF BACTERIAL AMINOACYL-TRNA SYNTHETASE | INHIBOX LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
| CN-110049970-A | 2- amino-N- (aryl sulfonyl kia)-acetamide compound of inhibitor as bacterium aminoacyl-TRNA synzyme | 牛津药物设计有限公司 | 2019-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11802110-B2 | 2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase | AARS1, NSUN3, GARS1 | TSHR 1674/4885APP 4192/4885CA12 4798/4885 |
| US-20200039929-A1 | 2-AMINO-N-(ARYLSULFINYL)-ACETAMIDE COMPOUNDS AS INHIBITORS OF BACTERIAL AMINOACYL-TRNA SYNTHETASE | AARS1, NSUN3, GARS1 | TSHR 1674/4885APP 4192/4885CA12 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.