Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847221 | 0.85 | TSHR (0.41) | TSHRAPPBRD4 | |
| SCHEMBL6848815 | 0.85 | TSHR (0.41) | TSHRAPPBRD4 | |
| SCHEMBL21691165 | 0.83 | TSHR (0.39) | TSHRAPPBRD4 | |
| Hydrochloric Acid SCHEMBL6841993 | 0.83 | TSHR (0.39) | TSHRAPPBRD4 | |
| SCHEMBL20048796 | 0.83 | TSHR (0.39) | TSHRAPPEGFRERBB2EPHB2 | |
| Hydrochloric Acid SCHEMBL6846381 | 0.83 | TSHR (0.39) | TSHRAPPBRD4 | |
| SCHEMBL20048797 | 0.83 | TSHR (0.39) | TSHRAPPBRD4 | |
| SCHEMBL628205 | 0.75 | TSHR (0.61) | TSHRAPPEGFRERBB2MEN1 | |
| SCHEMBL28015253 | 0.75 | KEAP1 (0.52) | TSHRNPC1POLBBRD4MAPK1 | |
| Hydrochloric Acid SCHEMBL5151093 | 0.73 | TSHR (0.58) | TSHRAPPEGFRERBB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295198-A1 | VANILLIN-DERIVED FLAME RETARDANT MONOMERS, RESINS, PREPOLYMERS, AND POLYMERS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295198-A1 | VANILLIN-DERIVED FLAME RETARDANT MONOMERS, RESINS, PREPOLYMERS, AND POLYMERS | PNN, PFAS, POLN | TSHR 4141/4885APP 1294/4885EGFR 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.