Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21691931 | 0.93 | MAP4K4 (0.44) | PDK2MAP4K4CHEK1CLK4GABRG2 | |
| SCHEMBL21691567 | 0.93 | MAP4K4 (0.44) | PDK2MAP4K4CHEK1CLK4GABRG2 | |
| SCHEMBL21693050 | 0.93 | ADRA2C (0.40) | ADRA2CPDK2MAP4K4ALOX5CHEK1 | |
| SCHEMBL21693031 | 0.92 | MAP4K4 (0.43) | PDK2MAP4K4CHEK1CLK4GABRG2 | |
| SCHEMBL21691581 | 0.92 | MAP4K4 (0.43) | PDK2MAP4K4CHEK1CLK4GABRG2 | |
| SCHEMBL21691687 | 0.91 | ALOX5 (0.48) | ADRA2CPDK2MAP4K4ALOX5CHEK1 | |
| SCHEMBL21693099 | 0.91 | PDK2 (0.38) | ADRA2CPDK2MAP4K4ALOX5CHEK1 | |
| SCHEMBL21693184 | 0.91 | CHEK1 (0.42) | ADRA2CPDK2MAP4K4ALOX5CHEK1 | |
| SCHEMBL21692516 | 0.91 | CHEK1 (0.42) | ADRA2CPDK2MAP4K4ALOX5CHEK1 | |
| SCHEMBL21691560 | 0.91 | MAP4K4 (0.42) | PDK2MAP4K4CHEK1CLK4GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053228-B2 | Condensed cyclic compound, composition including the condensed cyclic compound, and organic light-emitting device including the condensed cyclic compound | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2021-07-06 | — | — | US | disclosed |
| US-20200031812-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND | SAMSUNG SDI CO., LTD. (KR) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053228-B2 | Condensed cyclic compound, composition including the condensed cyclic compound, and organic light-emitting device including the condensed cyclic compound | CCNL2, ARL1, CRY1 | ADRA2C 776/4885PDK2 1990/4885MAP4K4 3404/4885 |
| US-20200031812-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND | CCNL2, ARL1, CRY1 | ADRA2C 776/4885PDK2 1990/4885MAP4K4 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.