Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899131 | 0.85 | KDM1A (0.51) | — | |
| SCHEMBL17899154 | 0.83 | PARP1 (0.42) | — | |
| SCHEMBL17931461 | 0.81 | ALDH1A1 (0.45) | — | |
| SCHEMBL17888665 | 0.78 | AKR1C3 (0.46) | SIRT2 | |
| SCHEMBL1758181 | 0.75 | CYP2C9 (0.55) | NAMPT | |
| Hydrochloric Acid SCHEMBL3630728 | 0.74 | CYP2C9 (0.54) | NAMPT | |
| SCHEMBL7263062 | 0.72 | SLC18A3 (0.52) | P2RY14NAMPT | |
| SCHEMBL16465164 | 0.72 | SYK (0.47) | SIRT2 | |
| SCHEMBL28051628 | 0.72 | CYP2C9 (0.51) | P2RY14 | |
| Hydrochloric Acid SCHEMBL4005490 | 0.71 | HTR2C (0.50) | P2RY14NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607944-A1 | NOVEL CYCLIN-DEPENDENT KINASE 8 AND/OR 19 INHIBITOR | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2020-02-12 | — | — | EP | disclosed |