SCHEMBL17899154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17899131	0.88	KDM1A (0.51)	PARP1EGFRLCKJAK3KDM1A
	SCHEMBL17931461	0.84	ALDH1A1 (0.45)	KDM1AMAOAKDM1BRCOR1SYK
	SCHEMBL21697446	0.83	KCNH2 (0.39)	PARP1EGFRLCKJAK3BTK
	SCHEMBL21697490	0.83	SIRT2 (0.45)	—
	SCHEMBL16304063	0.79	KCNH2 (0.54)	PARP1ESRRGKCNH2ESRRBESR1
	SCHEMBL5686231	0.76	SYK (0.50)	PARP1EGFRLCKJAK3BTK
	SCHEMBL25453173	0.75	HRH3 (0.55)	PARP1ESRRGKCNH2ESRRBESR1
	SCHEMBL17888665	0.74	AKR1C3 (0.46)	KDM1A
	SCHEMBL28833626	0.72	JAK3 (0.57)	PARP1EGFRLCKJAK3BTK
	SCHEMBL1306328	0.70	KCNH2 (0.58)	PARP1ESRRGKCNH2ESRRBESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.