Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25859740 | 1.00 | TPSAB1 (0.40) | TPSAB1PRSS1ABCB1ITGB1ITGA5 | |
| SCHEMBL19478671 | 0.87 | MMP2 (0.40) | TPSAB1PRSS1ABCB1ALDH1A1LMNA | |
| SCHEMBL23220190 | 0.84 | ABCB1 (0.42) | TPSAB1PRSS1ABCB1ITGB1ITGA5 | |
| SCHEMBL21952369 | 0.80 | ABCB1 (0.44) | TPSAB1PRSS1ABCB1ITGB1ITGA5 | |
| SCHEMBL24040106 | 0.80 | CTSB (0.40) | TPSAB1PRSS1ABCB1ITGB1ITGA5 | |
| SCHEMBL25100408 | 0.80 | ABCB1 (0.39) | TPSAB1PRSS1ABCB1ITGB1ITGA5 | |
| SCHEMBL22915323 | 0.79 | PARP10 (0.41) | TPSAB1PRSS1ABCB1ALDH1A1LMNA | |
| SCHEMBL7794342 | 0.77 | ABCB1 (0.50) | ABCB1ALDH1A1KMT2AHPGDMAPK1 | |
| SCHEMBL24336897 | 0.76 | MEN1 (0.47) | TPSAB1PRSS1PLGALDH1A1LMNA | |
| SCHEMBL19884607 | 0.76 | TPSAB1 (0.41) | TPSAB1PRSS1ABCB1PLGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3682904-A1 | SACCHARIDE DERIVATIVE OF A TOXIC PAYLOAD AND ANTIBODY CONJUGATES THEREOF | Glykos Finland Oy (FI) | 2020-07-22 | — | — | EP | disclosed |
| EP-3160513-B1 | SACCHARIDE DERIVATIVE OF A TOXIC PAYLOAD AND ANTIBODY CONJUGATES THEREOF | GLYKOS FINLAND OY (FI) | 2020-02-12 | — | — | EP | disclosed |