Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450335 | 0.85 | MEN1 (0.68) | KMT2ASMN1; SMN2TP53ESR2MEN1 | |
| SCHEMBL312513 | 0.81 | SMN1; SMN2 (0.75) | KMT2ASMN1; SMN2TP53ESR2MEN1 | |
| SCHEMBL4560026 | 0.81 | KMT2A (0.75) | KMT2ASMN1; SMN2TP53ESR2MEN1 | |
| SCHEMBL28175243 | 0.73 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2TP53ESR2MEN1 | |
| SCHEMBL14413761 | 0.73 | EPHX2 (0.62) | KMT2ASMN1; SMN2TP53ESR2MEN1 | |
| SCHEMBL1574694 | 0.72 | RAB9A (0.58) | SMN1; SMN2TP53KDM4ENAMPTALDH1A1 | |
| SCHEMBL14413645 | 0.72 | KDM4E (0.68) | KMT2ASMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL29663991 | 0.72 | RAB9A (0.76) | KMT2ASMN1; SMN2TP53ESR2MEN1 | |
| SCHEMBL21568088 | 0.72 | MAPT (0.71) | KMT2ASMN1; SMN2TP53ESR2MEN1 | |
| SCHEMBL24381790 | 0.71 | KDM4E (0.67) | KMT2ASMN1; SMN2TP53ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970340-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2020-02-12 | — | — | EP | disclosed |