Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21698459 | 0.85 | KMT2A (0.62) | MEN1KMT2ASMN1; SMN2TP53GAA | |
| SCHEMBL4560026 | 0.84 | KMT2A (0.75) | MEN1KMT2ASMN1; SMN2TP53GAA | |
| SCHEMBL312513 | 0.84 | SMN1; SMN2 (0.75) | MEN1KMT2ASMN1; SMN2TP53GAA | |
| SCHEMBL12994636 | 0.83 | TSHR (0.71) | KMT2ASMN1; SMN2TP53LMNAEPHX2 | |
| SCHEMBL11837576 | 0.82 | ALOX5 (0.69) | KMT2ASMN1; SMN2TP53GAALMNA | |
| SCHEMBL11839197 | 0.82 | SMN1; SMN2 (0.68) | KMT2ASMN1; SMN2GAALMNAEPHX2 | |
| SCHEMBL11833345 | 0.81 | LMNA (0.79) | SMN1; SMN2TP53LMNAEPHX2MAPT | |
| SCHEMBL12668447 | 0.81 | LMNA (0.64) | MEN1KMT2ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL14413882 | 0.79 | ALDH1A1 (0.64) | MEN1KMT2ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL14393776 | 0.78 | EPHX2 (0.70) | KMT2ASMN1; SMN2LMNAEPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773796-B1 | OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2010-03-03 | — | — | EP | disclosed |