SCHEMBL21699178

SCHEMBL21699178

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5c6c7ccccc7n(-c7ccccc7)c6n(-c6ccccc6)c5c4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
KMT2A Q03164 4/20 0.36
IL1R1 P14778 1/20 0.36
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 3/20 0.35
MAPT P10636 3/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 2/20 0.35
AVPR1A P37288 1/20 0.34
MAPK8 P45983 1/20 0.33
TSPO P30536 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
BRCA1 P38398 1/20 0.32
MAOB P27338 1/20 0.32
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21699226 0.99 L3MBTL1 (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21706880 0.99 L3MBTL1 (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21699186 0.99 L3MBTL1 (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21699167 0.97 KDM4E (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21706865 0.95 L3MBTL1 (0.37) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21699154 0.95 KDM4E (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21706879 0.93 KDM4E (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21699182 0.93 AVPR1A (0.35) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL21706831 0.92 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21699139 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608320-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND CONDENSED CYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed
US-20200052223-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-13 US disclosed
US-20200052224-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND CONDENSED CYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-13 US disclosed
EP-3608320-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND CONDENSED CYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2020-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052224-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND CONDENSED CYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE CTCF, SLCO4C1, SLC25A21 L3MBTL1 1652/4885KDM4E 2258/4885ATM 3611/4885
US-20200052223-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 L3MBTL1 1571/4885KDM4E 3395/4885ATM 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.