Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1058822 | 0.75 | — | — | |
| SCHEMBL16998591 | 0.74 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16254166 | 0.73 | — | — | |
| SCHEMBL23563382 | 0.70 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1PDE10AGAA | |
| SCHEMBL10031019 | 0.69 | PKM (0.51) | KMT2AMEN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12126153 | 0.69 | ALOX15 (0.55) | KMT2AMEN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12597510 | 0.69 | KMT2A (0.45) | KMT2AMEN1ALDH1A1PDE10AGAA | |
| SCHEMBL10039948 | 0.69 | KMT2A (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13510014 | 0.69 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1PDE10ASMN1; SMN2 | |
| SCHEMBL15705802 | 0.69 | KMT2A (0.53) | KMT2AMEN1GAAMAPK1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607821-A1 | COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES | Aerpio Therapeutics, Inc. (US) | 2020-02-12 | — | — | EP | disclosed |