Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.67 |
| ▸ | DRD4 | P21917 | 13/20 | 0.67 |
| ▸ | HTR1A | P08908 | 12/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21699882 | 0.84 | DRD2 (0.65) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL21661933 | 0.83 | DRD2 (0.59) | DRD2DRD4HTR1AKCNH2CARM1 | |
| Hydrochloric Acid SCHEMBL21642940 | 0.82 | DRD2 (0.58) | DRD2DRD4HTR1AKCNH2CARM1 | |
| SCHEMBL23714663 | 0.81 | DRD4 (0.59) | DRD2DRD4HTR1AKCNH2TLR9 | |
| SCHEMBL17888476 | 0.79 | DRD2 (0.53) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL21642942 | 0.77 | DRD2 (1.00) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL21662150 | 0.76 | DRD4 (1.00) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL13490648 | 0.76 | DRD2 (0.60) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL21662149 | 0.75 | DRD4 (1.00) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL21662153 | 0.75 | DRD2 (1.00) | DRD2DRD4HTR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608314-A1 | 2,6-DISUBSTITUTED PYRIDINE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-02-12 | — | — | EP | disclosed |